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BMI1 regulates multiple myeloma-associated macrophage’s pro-myeloma functions

Multiple myeloma (MM) is an aggressive malignancy characterized by terminally differentiated plasma cells accumulation in the bone marrow (BM). MM BM exhibits elevated MΦs (macrophages) numbers relative to healthy BM. Current evidence indicates that MM-MΦs (MM-associated macrophages) have pro-myelom...

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Detalles Bibliográficos
Autores principales: Zhang, Danfeng, Huang, Jingcao, Wang, Fangfang, Ding, Hong, Cui, Yushan, Yang, Yan, Xu, Juan, Luo, Hongmei, Gao, Yuhan, Pan, Ling, Wu, Yu, Gong, Yuping, Xie, Liping, Liu, Zhigang, Qu, Ying, Zhang, Li, Liu, Weiping, Zhang, Wenyan, Zhao, Sha, Yi, Qing, Niu, Ting, Zheng, Yuhuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124065/
https://www.ncbi.nlm.nih.gov/pubmed/33993198
http://dx.doi.org/10.1038/s41419-021-03748-y