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Long noncoding RNA LYPLAL1-AS1 regulates adipogenic differentiation of human mesenchymal stem cells by targeting desmoplakin and inhibiting the Wnt/β-catenin pathway

Long noncoding RNAs are crucial factors for modulating adipogenic differentiation, but only a few have been identified in humans. In the current study, we identified a previously unknown human long noncoding RNA, LYPLAL1-antisense RNA1 (LYPLAL1-AS1), which was dramatically upregulated during the adi...

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Detalles Bibliográficos
Autores principales: Yang, Yanlei, Fan, Junfen, Xu, Haoying, Fan, Linyuan, Deng, Luchan, Li, Jing, Li, Di, Li, Hongling, Zhang, Fengchun, Zhao, Robert Chunhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124068/
https://www.ncbi.nlm.nih.gov/pubmed/33993187
http://dx.doi.org/10.1038/s41420-021-00500-5