Multi-omic analysis elucidates the genetic basis of hydrocephalus

We conducted PrediXcan analysis of hydrocephalus risk in ten neurological tissues and whole blood. Decreased expression of MAEL in the brain was significantly associated (Bonferroni-adjusted p < 0.05) with hydrocephalus. PrediXcan analysis of brain imaging and genomics data in the independent UK...

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Detalles Bibliográficos
Autores principales: Hale, Andrew T., Bastarache, Lisa, Morales, Diego M., Wellons, John C., Limbrick, David D., Gamazon, Eric R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124085/
https://www.ncbi.nlm.nih.gov/pubmed/33951428
http://dx.doi.org/10.1016/j.celrep.2021.109085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124085/
https://www.ncbi.nlm.nih.gov/pubmed/33951428
http://dx.doi.org/10.1016/j.celrep.2021.109085

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