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Multi-omic analysis elucidates the genetic basis of hydrocephalus
We conducted PrediXcan analysis of hydrocephalus risk in ten neurological tissues and whole blood. Decreased expression of MAEL in the brain was significantly associated (Bonferroni-adjusted p < 0.05) with hydrocephalus. PrediXcan analysis of brain imaging and genomics data in the independent UK...
Autores principales: | Hale, Andrew T., Bastarache, Lisa, Morales, Diego M., Wellons, John C., Limbrick, David D., Gamazon, Eric R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124085/ https://www.ncbi.nlm.nih.gov/pubmed/33951428 http://dx.doi.org/10.1016/j.celrep.2021.109085 |
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