Cocrystal of Apixaban–Quercetin: Improving Solubility and Bioavailability of Drug Combination of Two Poorly Soluble Drugs

Drug combinations have been the hotspot of the pharmaceutical industry, but the promising applications are limited by the unmet solubility and low bioavailability. In this work, novel cocrystals, consisting of two antithrombotic drugs with poor solubility and low bioavailability in vivo, namely, api...

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Detalles Bibliográficos
Autores principales: Zhang, Li, Kong, Dewen, Wang, Hongjuan, Jiao, Lingtai, Zhao, Xiaoyue, Song, Junke, Yang, Dezhi, Yang, Haiguang, Yang, Shiying, Du, Guanhua, Lu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124247/
https://www.ncbi.nlm.nih.gov/pubmed/34063645
http://dx.doi.org/10.3390/molecules26092677

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124247/
https://www.ncbi.nlm.nih.gov/pubmed/34063645
http://dx.doi.org/10.3390/molecules26092677

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