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Evaluation of Glutaminase Expression in Prostate Adenocarcinoma and Correlation with Clinicopathologic Parameters

SIMPLE SUMMARY: High expression levels of glutaminase (GLS1) are reported for several cancers, and correlate with parameters of disease status. GLS1, the rate-limiting enzyme in the glutamine pathway, is involved in DNA/RNA and amino acid synthesis and contributes to other pathways (e.g., TCA cycle)...

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Detalles Bibliográficos
Autores principales: Myint, Zin W., Sun, Ramon C., Hensley, Patrick J., James, Andrew C., Wang, Peng, Strup, Stephen E., McDonald, Robert J., Yan, Donglin, St. Clair, William H., Allison, Derek B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124252/
https://www.ncbi.nlm.nih.gov/pubmed/33947068
http://dx.doi.org/10.3390/cancers13092157