Advances in Predictions of Oral Bioavailability of Candidate Drugs in Man with New Machine Learning Methodology

Oral bioavailability (F) is an essential determinant for the systemic exposure and dosing regimens of drug candidates. F is determined by numerous processes, and computational predictions of human estimates have so far shown limited results. We describe a new methodology where F in humans is predict...

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Detalles Bibliográficos
Autores principales: Fagerholm, Urban, Hellberg, Sven, Spjuth, Ola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124353/
https://www.ncbi.nlm.nih.gov/pubmed/33925103
http://dx.doi.org/10.3390/molecules26092572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124353/
https://www.ncbi.nlm.nih.gov/pubmed/33925103
http://dx.doi.org/10.3390/molecules26092572

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