Cargando…
Advances in Predictions of Oral Bioavailability of Candidate Drugs in Man with New Machine Learning Methodology
Oral bioavailability (F) is an essential determinant for the systemic exposure and dosing regimens of drug candidates. F is determined by numerous processes, and computational predictions of human estimates have so far shown limited results. We describe a new methodology where F in humans is predict...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124353/ https://www.ncbi.nlm.nih.gov/pubmed/33925103 http://dx.doi.org/10.3390/molecules26092572 |