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Effect of Whole Tissue Culture and Basic Fibroblast Growth Factor on Maintenance of Tie2 Molecule Expression in Human Nucleus Pulposus Cells

Previous work showed a link between Tie2(+) nucleus pulposus progenitor cells (NPPC) and disc degeneration. However, NPPC remain difficult to maintain in culture. Here, we report whole tissue culture (WTC) combined with fibroblast growth factor 2 (FGF2) and chimeric FGF (cFGF) supplementation to sup...

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Detalles Bibliográficos
Autores principales: Sako, Kosuke, Sakai, Daisuke, Nakamura, Yoshihiko, Schol, Jordy, Matsushita, Erika, Warita, Takayuki, Horikita, Natsumi, Sato, Masato, Watanabe, Masahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124367/
https://www.ncbi.nlm.nih.gov/pubmed/33946902
http://dx.doi.org/10.3390/ijms22094723