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A Proteomic Approach for Systematic Mapping of Substrates of Human Deubiquitinating Enzymes

The human genome contains nearly 100 deubiquitinating enzymes (DUBs) responsible for removing ubiquitin moieties from a large variety of substrates. Which DUBs are responsible for targeting which substrates remain mostly unknown. Here we implement the (bio)Ub approach to identify DUB substrates in a...

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Detalles Bibliográficos
Autores principales: Ramirez, Juanma, Prieto, Gorka, Olazabal-Herrero, Anne, Borràs, Eva, Fernandez-Vigo, Elvira, Alduntzin, Unai, Osinalde, Nerea, Beaskoetxea, Javier, Lectez, Benoit, Aloria, Kerman, Rodriguez, Jose Antonio, Paradela, Alberto, Sabidó, Eduard, Muñoz, Javier, Corrales, Fernando, Arizmendi, Jesus M., Mayor, Ugo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124392/
https://www.ncbi.nlm.nih.gov/pubmed/34063716
http://dx.doi.org/10.3390/ijms22094851