Myocardial Hypertrophy and Fibrosis Are Associated with Cardiomyocyte Beta-Catenin and TRPC6/Calcineurin/NFAT Signaling in Spontaneously Hypertensive Rats with 5/6 Nephrectomy

Background: Arterial hypertension (AH) is associated with heart and chronic kidney disease (CKD). However, the precise mechanisms of myocardial remodeling (MR) in the settings of CKD remain elusive. We hypothesized that TRPC6, calcineurin/NFAT, and Wnt/β-catenin signaling pathways are involved in th...

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Detalles Bibliográficos
Autores principales: Bogdanova, Evdokia, Beresneva, Olga, Galkina, Olga, Zubina, Irina, Ivanova, Galina, Parastaeva, Marina, Semenova, Natalia, Dobronravov, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124394/
https://www.ncbi.nlm.nih.gov/pubmed/33924991
http://dx.doi.org/10.3390/ijms22094645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124394/
https://www.ncbi.nlm.nih.gov/pubmed/33924991
http://dx.doi.org/10.3390/ijms22094645

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