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Effects of Thrombomodulin in Reducing Lethality and Suppressing Neutrophil Extracellular Trap Formation in the Lungs and Liver in a Lipopolysaccharide-Induced Murine Septic Shock Model

Neutrophil extracellular trap (NET) formation, an innate immune system response, is associated with thrombogenesis and vascular endothelial injury. Circulatory disorders due to microvascular thrombogenesis are one of the principal causes of organ damage. NET formation in organs contributes to the ex...

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Detalles Bibliográficos
Autores principales: Kato, Yu, Nishida, Osamu, Kuriyama, Naohide, Nakamura, Tomoyuki, Kawaji, Takahiro, Onouchi, Takanori, Hasegawa, Daisuke, Shimomura, Yasuyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124404/
https://www.ncbi.nlm.nih.gov/pubmed/34066510
http://dx.doi.org/10.3390/ijms22094933