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Effects of Thrombomodulin in Reducing Lethality and Suppressing Neutrophil Extracellular Trap Formation in the Lungs and Liver in a Lipopolysaccharide-Induced Murine Septic Shock Model
Neutrophil extracellular trap (NET) formation, an innate immune system response, is associated with thrombogenesis and vascular endothelial injury. Circulatory disorders due to microvascular thrombogenesis are one of the principal causes of organ damage. NET formation in organs contributes to the ex...
Autores principales: | Kato, Yu, Nishida, Osamu, Kuriyama, Naohide, Nakamura, Tomoyuki, Kawaji, Takahiro, Onouchi, Takanori, Hasegawa, Daisuke, Shimomura, Yasuyo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124404/ https://www.ncbi.nlm.nih.gov/pubmed/34066510 http://dx.doi.org/10.3390/ijms22094933 |
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