Cancer-Associated Fibroblast-Derived IL-6 Determines Unfavorable Prognosis in Cholangiocarcinoma by Affecting Autophagy-Associated Chemoresponse

SIMPLE SUMMARY: We aimed to validate with clinical and molecular data the hypothesis that CAF infiltration and release of IL-6 predict poor prognosis in CCA patients following dysregulation of autophagy in cancer cells. Stromal IL-6 and cancer-cell-associated autophagy proteins were assayed by Tissu...

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Detalles Bibliográficos
Autores principales: Thongchot, Suyanee, Vidoni, Chiara, Ferraresi, Alessandra, Loilome, Watcharin, Khuntikeo, Narong, Sangkhamanon, Sakkarn, Titapun, Attapol, Isidoro, Ciro, Namwat, Nisana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124468/
https://www.ncbi.nlm.nih.gov/pubmed/33925189
http://dx.doi.org/10.3390/cancers13092134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124468/
https://www.ncbi.nlm.nih.gov/pubmed/33925189
http://dx.doi.org/10.3390/cancers13092134

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