Identification of SYS1 as a Host Factor Required for Shiga Toxin-Mediated Cytotoxicity in Vero Cells

Shiga toxin (STx) or Vero toxin is a virulence factor produced by enterohemorrhagic Escherichia coli. The toxin binds to the glycosphingolipid globotriaosylceramide (Gb3) for its entry, and causes cell death by inhibiting ribosome function. Previously, we performed a loss-of-function screen in HeLa...

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Detalles Bibliográficos
Autores principales: Sakuma, Chisato, Sekizuka, Tsuyoshi, Kuroda, Makoto, Hanada, Kentaro, Yamaji, Toshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124574/
https://www.ncbi.nlm.nih.gov/pubmed/34066520
http://dx.doi.org/10.3390/ijms22094936

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124574/
https://www.ncbi.nlm.nih.gov/pubmed/34066520
http://dx.doi.org/10.3390/ijms22094936

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