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Preclinical Assessment Addressing Intravenous Administration of a [(68)Ga]Ga-PSMA-617 Microemulsion: Acute In Vivo Toxicity, Tolerability, PET Imaging, and Biodistribution

It has been herein presented that a microemulsion, known to be an effective and safe drug delivery system following intravenous administration, can be loaded with traces of [(68)Ga]Ga-PSMA-617 without losing its properties or causing toxicity. Following tolerated IV injections the capability of the...

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Detalles Bibliográficos
Autores principales: Mandiwana, Vusani, Kalombo, Lonji, Hayeshi, Rose, Zeevaart, Jan Rijn, Ebenhan, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124668/
https://www.ncbi.nlm.nih.gov/pubmed/33946599
http://dx.doi.org/10.3390/molecules26092650