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Isolation and Characterization of Human Colon Adenocarcinoma Stem-Like Cells Based on the Endogenous Expression of the Stem Markers

Background: Cancer stem cells’ (CSCs) self-maintenance is regulated via the pluripotency pathways promoting the most aggressive tumor phenotype. This study aimed to use the activity of these pathways for the CSCs’ subpopulation enrichment and separating cells characterized by the OCT4 and SOX2 expre...

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Detalles Bibliográficos
Autores principales: Koshkin, Sergei A., Anatskaya, Olga V., Vinogradov, Alexander E., Uversky, Vladimir N., Dayhoff, Guy W., Bystriakova, Margarita A., Pospelov, Valery A., Tolkunova, Elena N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124683/
https://www.ncbi.nlm.nih.gov/pubmed/33925224
http://dx.doi.org/10.3390/ijms22094682