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Isolation and Characterization of Human Colon Adenocarcinoma Stem-Like Cells Based on the Endogenous Expression of the Stem Markers
Background: Cancer stem cells’ (CSCs) self-maintenance is regulated via the pluripotency pathways promoting the most aggressive tumor phenotype. This study aimed to use the activity of these pathways for the CSCs’ subpopulation enrichment and separating cells characterized by the OCT4 and SOX2 expre...
Autores principales: | Koshkin, Sergei A., Anatskaya, Olga V., Vinogradov, Alexander E., Uversky, Vladimir N., Dayhoff, Guy W., Bystriakova, Margarita A., Pospelov, Valery A., Tolkunova, Elena N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124683/ https://www.ncbi.nlm.nih.gov/pubmed/33925224 http://dx.doi.org/10.3390/ijms22094682 |
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