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Functional Roles of PARP2 in Assembling Protein–Protein Complexes Involved in Base Excision DNA Repair

Poly(ADP-ribose) polymerase 2 (PARP2) participates in base excision repair (BER) alongside PARP1, but its functions are still under study. Here, we characterize binding affinities of PARP2 for other BER proteins (PARP1, APE1, Polβ, and XRCC1) and oligomerization states of the homo- and hetero-associ...

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Detalles Bibliográficos
Autores principales: Vasil’eva, Inna, Moor, Nina, Anarbaev, Rashid, Kutuzov, Mikhail, Lavrik, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124814/
https://www.ncbi.nlm.nih.gov/pubmed/33925170
http://dx.doi.org/10.3390/ijms22094679