Homologous Recombination Repair Deficiency and Implications for Tumor Immunogenicity

SIMPLE SUMMARY: Cells possess several pathways that repair DNA damage. One of these pathways is homologous recombination repair (HR), a pathway responsible for the repair of double-strand DNA breaks. In cancer, HR is sometimes dysfunctional, leading to genomic instability. The genomic instability ob...

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Detalles Bibliográficos
Autores principales: van Wilpe, Sandra, Tolmeijer, Sofie H., Koornstra, Rutger H. T., de Vries, I. Jolanda M., Gerritsen, Winald R., Ligtenberg, Marjolijn, Mehra, Niven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124836/
https://www.ncbi.nlm.nih.gov/pubmed/34067105
http://dx.doi.org/10.3390/cancers13092249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124836/
https://www.ncbi.nlm.nih.gov/pubmed/34067105
http://dx.doi.org/10.3390/cancers13092249

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