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Pharmacological Inhibition of miR-130 Family Suppresses Bladder Tumor Growth by Targeting Various Oncogenic Pathways via PTPN1

Previously, we have revealed that the miR-130 family (miR-130b, miR-301a, and miR-301b) functions as an oncomiR in bladder cancer. The pharmacological inhibition of the miR-130 family molecules by the seed-targeting strategy with an 8-mer tiny locked nucleic acid (LNA) inhibits the growth, migration...

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Detalles Bibliográficos
Autores principales: Monoe, Yuya, Jingushi, Kentaro, Kawase, Akitaka, Hirono, Takayuki, Hirose, Ryo, Nakatsuji, Yoshino, Kitae, Kaori, Ueda, Yuko, Hase, Hiroaki, Abe, Yuichi, Adachi, Jun, Tomonaga, Takeshi, Tsujikawa, Kazutake
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124864/
https://www.ncbi.nlm.nih.gov/pubmed/33947152
http://dx.doi.org/10.3390/ijms22094751