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ATRX Alteration Contributes to Tumor Growth and Immune Escape in Pleomorphic Sarcomas
SIMPLE SUMMARY: There is still no efficient systemic treatment for pleomorphic sarcomas. This study shows that 1/4 of them have an ATRX alteration that diminishes the immune response. This phenotype is related to the inhibition of mast cell recruitment upon ATRX alteration, which could be targeted t...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124877/ https://www.ncbi.nlm.nih.gov/pubmed/33946962 http://dx.doi.org/10.3390/cancers13092151 |