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Size-Exclusion Chromatography Separation Reveals That Vesicular and Non-Vesicular Small RNA Profiles Differ in Cell Free Urine

Urinary extracellular vesicles (EVs) and their RNA cargo are a novel source of biomarkers for various diseases. We aimed to identify the optimal method for isolating small (<200 nm) EVs from human urine prior to small RNA analysis. EVs from filtered healthy volunteer urine were concentrated using...

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Detalles Bibliográficos
Autores principales: Karttunen, Jenni, Stewart, Sarah E., Kalmar, Lajos, Grant, Andrew J., Karet Frankl, Fiona E., Williams, Tim L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124894/
https://www.ncbi.nlm.nih.gov/pubmed/34063036
http://dx.doi.org/10.3390/ijms22094881