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Genes Implicated in Familial Parkinson’s Disease Provide a Dual Picture of Nigral Dopaminergic Neurodegeneration with Mitochondria Taking Center Stage

The mechanism of nigral dopaminergic neuronal degeneration in Parkinson’s disease (PD) is unknown. One of the pathological characteristics of the disease is the deposition of α-synuclein (α-syn) that occurs in the brain from both familial and sporadic PD patients. This paper constitutes a narrative...

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Detalles Bibliográficos
Autores principales: Franco, Rafael, Rivas-Santisteban, Rafael, Navarro, Gemma, Pinna, Annalisa, Reyes-Resina, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124903/
https://www.ncbi.nlm.nih.gov/pubmed/33924963
http://dx.doi.org/10.3390/ijms22094643