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Targeting Mitochondrial Metabolism in Clear Cell Carcinoma of the Ovaries

Ovarian clear cell carcinoma (OCCC) is a rare but chemorefractory tumor. About 50% of all OCCC patients have inactivating mutations of ARID1A, a member of the SWI/SNF chromatin-remodeling complex. Members of the SWI/SNF remodeling have emerged as regulators of the energetic metabolism of mammalian c...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaonan, Shetty, Mihir, Clemente, Valentino, Linder, Stig, Bazzaro, Martina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124918/
https://www.ncbi.nlm.nih.gov/pubmed/33947138
http://dx.doi.org/10.3390/ijms22094750