Investigation of Antifungal Properties of Synthetic Dimethyl-4-Bromo-1-(Substituted Benzoyl) Pyrrolo[1,2-a] Quinoline-2,3-Dicarboxylates Analogues: Molecular Docking Studies and Conceptual DFT-Based Chemical Reactivity Descriptors and Pharmacokinetics Evaluation

Candida albicans, an opportunistic fungal pathogen, frequently colonizes immune-compromised patients and causes mild to severe systemic reactions. Only few antifungal drugs are currently in use for therapeutic treatment. However, evolution of a drug-resistant C. albicans fungal pathogen is of major...

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Detalles Bibliográficos
Autores principales: Uppar, Vijayakumar, Chandrashekharappa, Sandeep, Shivamallu, Chandan, P, Sushma, Kollur, Shiva Prasad, Ortega-Castro, Joaquín, Frau, Juan, Flores-Holguín, Norma, Basarikatti, Atiyaparveen I., Chougala, Mallikarjun, Mohan M, Mrudula, Banuprakash, Govindappa, Jayadev, Venugopala, Katharigatta N., Nandeshwarappa, Belakatte P., Veerapur, Ravindra, Al-Kheraif, Abdulaziz A., Elgorban, Abdallah M., Syed, Asad, Mudnakudu-Nagaraju, Kiran K., Padmashali, Basavaraj, Glossman-Mitnik, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124935/
https://www.ncbi.nlm.nih.gov/pubmed/34066433
http://dx.doi.org/10.3390/molecules26092722

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124935/
https://www.ncbi.nlm.nih.gov/pubmed/34066433
http://dx.doi.org/10.3390/molecules26092722

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