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Integration of Metabolomics and Gene Expression Profiling Elucidates IL4I1 as Modulator of Ibrutinib Resistance in ABC-Diffuse Large B Cell Lymphoma

SIMPLE SUMMARY: In this study, we present a workflow to understand the modulator of ibrutinib resistance in ABC diffuse large B cell lymphoma by integrating Metabolomics and Gene expression profiling as shown in the graphical abstract. We performed an untargeted metabolomics analysis using a Q-Exact...

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Detalles Bibliográficos
Autores principales: Choueiry, Fouad, Singh, Satishkumar, Sircar, Anuvrat, Laliotis, Georgios, Sun, Xiaowei, Chavdoula, Evangelia, Zhang, Shiqi, Helmig-Mason, JoBeth, Hart, Amber, Epperla, Narendranath, Tsichlis, Philip, Baiocchi, Robert, Alinari, Lapo, Zhu, Jiangjiang, Sehgal, Lalit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124963/
https://www.ncbi.nlm.nih.gov/pubmed/33946867
http://dx.doi.org/10.3390/cancers13092146