Cargando…
Integration of Metabolomics and Gene Expression Profiling Elucidates IL4I1 as Modulator of Ibrutinib Resistance in ABC-Diffuse Large B Cell Lymphoma
SIMPLE SUMMARY: In this study, we present a workflow to understand the modulator of ibrutinib resistance in ABC diffuse large B cell lymphoma by integrating Metabolomics and Gene expression profiling as shown in the graphical abstract. We performed an untargeted metabolomics analysis using a Q-Exact...
Autores principales: | Choueiry, Fouad, Singh, Satishkumar, Sircar, Anuvrat, Laliotis, Georgios, Sun, Xiaowei, Chavdoula, Evangelia, Zhang, Shiqi, Helmig-Mason, JoBeth, Hart, Amber, Epperla, Narendranath, Tsichlis, Philip, Baiocchi, Robert, Alinari, Lapo, Zhu, Jiangjiang, Sehgal, Lalit |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124963/ https://www.ncbi.nlm.nih.gov/pubmed/33946867 http://dx.doi.org/10.3390/cancers13092146 |
Ejemplares similares
-
Exploiting the fibroblast growth factor receptor-1 vulnerability to therapeutically restrict the MYC-EZH2-CDKN1C axis-driven proliferation in Mantle cell lymphoma
por: Sircar, Anuvrat, et al.
Publicado: (2023) -
Impact and Intricacies of Bone Marrow Microenvironment in B-cell Lymphomas: From Biology to Therapy
por: Sircar, Anuvrat, et al.
Publicado: (2020) -
Transcriptional regulation of amino acid metabolism by KDM2B, in the context of ncPRC1.1 and in concert with MYC and ATF4
por: Chavdoula, Evangelia, et al.
Publicado: (2023) -
Ibrutinib Resistance Mechanisms and Treatment Strategies for B-Cell Lymphomas
por: George, Bhawana, et al.
Publicado: (2020) -
Management of relapsed/refractory marginal zone lymphoma: focus on ibrutinib
por: Denlinger, Nathan M, et al.
Publicado: (2018)