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Mechanisms of PD-L1 Regulation in Malignant and Virus-Infected Cells

Programmed cell death protein 1 (PD-1), a receptor on T cells, and its ligand, PD-L1, have been a topic of much interest in cancer research. Both tumour and virus-infected cells can upregulate PD-L1 to suppress cytotoxic T-cell killing. Research on the PD-1/PD-L1 axis has led to the development of a...

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Detalles Bibliográficos
Autores principales: Farrukh, Hadia, El-Sayes, Nader, Mossman, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124996/
https://www.ncbi.nlm.nih.gov/pubmed/34063096
http://dx.doi.org/10.3390/ijms22094893