Effects of Simvastatin on Lipid Metabolism in Wild-Type Mice and Mice with Muscle PGC-1α Overexpression

Previous studies suggest that statins may disturb skeletal muscle lipid metabolism potentially causing lipotoxicity with insulin resistance. We investigated this possibility in wild-type mice (WT) and mice with skeletal muscle PGC-1α overexpression (PGC-1α OE mice). In WT mice, simvastatin had only...

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Detalles Bibliográficos
Autores principales: Panajatovic, Miljenko V., Singh, Francois, Krähenbühl, Stephan, Bouitbir, Jamal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125015/
https://www.ncbi.nlm.nih.gov/pubmed/34066911
http://dx.doi.org/10.3390/ijms22094950

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125015/
https://www.ncbi.nlm.nih.gov/pubmed/34066911
http://dx.doi.org/10.3390/ijms22094950

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