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Proteomic and Transcriptomic Analysis of Microviridae φX174 Infection Reveals Broad Upregulation of Host Escherichia coli Membrane Damage and Heat Shock Responses

Measuring host-bacteriophage dynamics is an important approach to understanding bacterial survival functions and responses to infection. The model Microviridae bacteriophage φX174 is endemic to the human gut and has been studied for over 70 years, but the host response to infection has never been in...

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Detalles Bibliográficos
Autores principales: Wright, Bradley W., Logel, Dominic Y., Mirzai, Mehdi, Pascovici, Dana, Molloy, Mark P., Jaschke, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125068/
https://www.ncbi.nlm.nih.gov/pubmed/33975962
http://dx.doi.org/10.1128/mSystems.00046-21