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Mycobacteria Tolerate Carbon Monoxide by Remodeling Their Respiratory Chain

Carbon monoxide (CO) gas is infamous for its acute toxicity. This toxicity predominantly stems from its tendency to form carbonyl complexes with transition metals, thus inhibiting the heme-prosthetic groups of proteins, including respiratory terminal oxidases. While CO has been proposed as an antiba...

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Detalles Bibliográficos
Autores principales: Bayly, Katherine, Cordero, Paul R. F., Kropp, Ashleigh, Huang, Cheng, Schittenhelm, Ralf B., Grinter, Rhys, Greening, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125079/
https://www.ncbi.nlm.nih.gov/pubmed/33975973
http://dx.doi.org/10.1128/mSystems.01292-20