Properties of Non-Aminoglycoside Compounds Used to Stimulate Translational Readthrough of PTC Mutations in Primary Ciliary Dyskinesia

Primary ciliary dyskinesia (PCD) is a rare disease with autosomal recessive inheritance, caused mostly by bi-allelic gene mutations that impair motile cilia structure and function. Currently, there are no causal treatments for PCD. In many disease models, translational readthrough of premature termi...

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Detalles Bibliográficos
Autores principales: Dabrowski, Maciej, Bukowy-Bieryllo, Zuzanna, Jackson, Claire L., Zietkiewicz, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125088/
https://www.ncbi.nlm.nih.gov/pubmed/34066907
http://dx.doi.org/10.3390/ijms22094923

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125088/
https://www.ncbi.nlm.nih.gov/pubmed/34066907
http://dx.doi.org/10.3390/ijms22094923

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