Synthesis, Structure, Carbohydrate Enzyme Inhibition, Antioxidant Activity, In Silico Drug-Receptor Interactions and Drug-Like Profiling of the 5-Styryl-2-Aminochalcone Hybrids

The 2-amino-5-(3/4-fluorostyryl)acetophenones were prepared and reacted with benzaldehyde derivatives to afford the corresponding 5-styryl-2-aminochalcone hybrids. The trans geometry of the styryl and α,β-unsaturated carbonyl arms, and the presence of NH(…)O intramolecular hydrogen bond were validat...

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Detalles Bibliográficos
Autores principales: Mphahlele, Malose J., Agbo, Emmanuel Ndubuisi, Choong, Yee Siew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125089/
https://www.ncbi.nlm.nih.gov/pubmed/34064448
http://dx.doi.org/10.3390/molecules26092692

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125089/
https://www.ncbi.nlm.nih.gov/pubmed/34064448
http://dx.doi.org/10.3390/molecules26092692

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