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Effect of Alpha-1 Antitrypsin on CFTR Levels in Primary Human Airway Epithelial Cells Grown at the Air-Liquid-Interface

The cystic fibrosis transmembrane conductance regulator (CFTR) gene is influenced by the fundamental cellular processes like epithelial differentiation/polarization, regeneration and epithelial–mesenchymal transition. Defects in CFTR protein levels and/or function lead to decreased airway surface li...

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Detalles Bibliográficos
Autores principales: Stanke, Frauke, Janciauskiene, Sabina, Tamm, Stephanie, Wrenger, Sabine, Raddatz, Ellen Luise, Jonigk, Danny, Braubach, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125203/
https://www.ncbi.nlm.nih.gov/pubmed/33946490
http://dx.doi.org/10.3390/molecules26092639