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Crystal Structure of Escherichia coli Agmatinase: Catalytic Mechanism and Residues Relevant for Substrate Specificity

Agmatine is the product of the decarboxylation of L-arginine by the enzyme arginine decarboxylase. This amine has been attributed to neurotransmitter functions, anticonvulsant, anti-neurotoxic, and antidepressant in mammals and is a potential therapeutic agent for diseases such as Alzheimer’s, Parki...

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Detalles Bibliográficos
Autores principales: Maturana, Pablo, Orellana, María S., Herrera, Sixto M., Martínez, Ignacio, Figueroa, Maximiliano, Martínez-Oyanedel, José, Castro-Fernandez, Victor, Uribe, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125230/
https://www.ncbi.nlm.nih.gov/pubmed/33946272
http://dx.doi.org/10.3390/ijms22094769