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Alzheimer’s Disease—Rationales for Potential Treatment with the Thrombin Inhibitor Dabigatran
Alzheimer’s disease (AD) is caused by neurodegenerative, but also vascular and hemostatic changes in the brain. The oral thrombin inhibitor dabigatran, which has been used for over a decade in preventing thromboembolism and has a well-known pharmacokinetic, safety and antidote profile, can be an opt...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125318/ https://www.ncbi.nlm.nih.gov/pubmed/33946588 http://dx.doi.org/10.3390/ijms22094805 |