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Tryptophan Metabolites at the Crossroad of Immune-Cell Interaction via the Aryl Hydrocarbon Receptor: Implications for Tumor Immunotherapy

The Aryl hydrocarbon receptor (AhR) is a critical regulator of both innate and adaptive immune responses, with potent immunomodulatory effects that makes this receptor an attractive molecular target for novel therapeutics. Accumulating evidence indicates that diverse—both host’s and microbial—trypto...

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Detalles Bibliográficos
Autores principales: Gargaro, Marco, Manni, Giorgia, Scalisi, Giulia, Puccetti, Paolo, Fallarino, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125364/
https://www.ncbi.nlm.nih.gov/pubmed/33924971
http://dx.doi.org/10.3390/ijms22094644