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TET2 Inhibits PD-L1 Gene Expression in Breast Cancer Cells through Histone Deacetylation

SIMPLE SUMMARY: Programmed cell death ligand 1 (PD-L1) is an essential immune checkpoint molecule that helps tumor cells to escape the immune surveillance. The aim of the current study was to investigate the epigenetic mechanisms underlying the aberrant expression of PD-L1 in breast cancer cells. He...

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Detalles Bibliográficos
Autores principales: Shen, Yinghui, Liu, Lu, Wang, Mengyuan, Xu, Bo, Lyu, Ruitu, Shi, Yujiang Geno, Tan, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125390/
https://www.ncbi.nlm.nih.gov/pubmed/34064441
http://dx.doi.org/10.3390/cancers13092207