The Kynurenic Acid Analog SZR72 Enhances Neuronal Activity after Asphyxia but Is Not Neuroprotective in a Translational Model of Neonatal Hypoxic Ischemic Encephalopathy

Hypoxic–ischemic encephalopathy (HIE) remains to be a major cause of long-term neurodevelopmental deficits in term neonates. Hypothermia offers partial neuroprotection warranting research for additional therapies. Kynurenic acid (KYNA), an endogenous product of tryptophan metabolism, was previously...

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Detalles Bibliográficos
Autores principales: Kovács, Viktória, Remzső, Gábor, Körmöczi, Tímea, Berkecz, Róbert, Tóth-Szűki, Valéria, Pénzes, Andrea, Vécsei, László, Domoki, Ferenc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125407/
https://www.ncbi.nlm.nih.gov/pubmed/34062911
http://dx.doi.org/10.3390/ijms22094822

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125407/
https://www.ncbi.nlm.nih.gov/pubmed/34062911
http://dx.doi.org/10.3390/ijms22094822

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