Species-Specific Regulation of TRPM2 by PI(4,5)P(2) via the Membrane Interfacial Cavity

The human apoptosis channel TRPM2 is stimulated by intracellular ADR-ribose and calcium. Recent studies show pronounced species-specific activation mechanisms. Our aim was to analyse the functional effect of phosphatidylinositol 4,5-bisphosphate (PI(4,5)P(2)), commonly referred to as PIP(2), on diff...

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Detalles Bibliográficos
Autores principales: Barth, Daniel, Lückhoff, Andreas, Kühn, Frank J. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125603/
https://www.ncbi.nlm.nih.gov/pubmed/33924946
http://dx.doi.org/10.3390/ijms22094637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125603/
https://www.ncbi.nlm.nih.gov/pubmed/33924946
http://dx.doi.org/10.3390/ijms22094637

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