Molecular Mechanisms Underlying TDP-43 Pathology in Cellular and Animal Models of ALS and FTLD

Amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) are neurodegenerative disorders that exist on a disease spectrum due to pathological, clinical and genetic overlap. In up to 97% of ALS cases and ~50% of FTLD cases, the primary pathological protein observed in affected...

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Detalles Bibliográficos
Autores principales: Wood, Alistair, Gurfinkel, Yuval, Polain, Nicole, Lamont, Wesley, Lyn Rea, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125728/
https://www.ncbi.nlm.nih.gov/pubmed/33946763
http://dx.doi.org/10.3390/ijms22094705

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125728/
https://www.ncbi.nlm.nih.gov/pubmed/33946763
http://dx.doi.org/10.3390/ijms22094705

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