Site-Specific Conversion of Cysteine in a Protein to Dehydroalanine Using 2-Nitro-5-thiocyanatobenzoic Acid

Dehydroalanine exists natively in certain proteins and can also be chemically made from the protein cysteine. As a strong Michael acceptor, dehydroalanine in proteins has been explored to undergo reactions with different thiolate reagents for making close analogues of post-translational modification...

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Detalles Bibliográficos
Autores principales: Qiao, Yuchen, Yu, Ge, Leeuwon, Sunshine Z., Liu, Wenshe Ray
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125731/
https://www.ncbi.nlm.nih.gov/pubmed/33947165
http://dx.doi.org/10.3390/molecules26092619

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125731/
https://www.ncbi.nlm.nih.gov/pubmed/33947165
http://dx.doi.org/10.3390/molecules26092619

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