Cargando…

Site-Specific Conversion of Cysteine in a Protein to Dehydroalanine Using 2-Nitro-5-thiocyanatobenzoic Acid

Dehydroalanine exists natively in certain proteins and can also be chemically made from the protein cysteine. As a strong Michael acceptor, dehydroalanine in proteins has been explored to undergo reactions with different thiolate reagents for making close analogues of post-translational modification...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qiao, Yuchen, Yu, Ge, Leeuwon, Sunshine Z., Liu, Wenshe Ray
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125731/ https://www.ncbi.nlm.nih.gov/pubmed/33947165 http://dx.doi.org/10.3390/molecules26092619

Ejemplares similares

Reductive opening of a cyclopropane ring in the Ni(II) coordination environment: a route to functionalized dehydroalanine and cysteine derivatives
por: Levitskiy, Oleg A, et al.
Publicado: (2022)

Chemical generation and modification of peptides containing multiple dehydroalanines
por: Morrison, Philip M., et al.
Publicado: (2015)

Human protein aging: modification and crosslinking through dehydroalanine and dehydrobutyrine intermediates
por: Wang, Zhen, et al.
Publicado: (2014)

Catalytic Modification of Dehydroalanine in Peptides and Proteins by Palladium‐Mediated Cross‐Coupling
por: de Bruijn, A. Dowine, et al.
Publicado: (2018)

Application of dehydroalanine as a building block for the synthesis of selenocysteine-containing peptides
por: Reddy, Kishorkumar M., et al.
Publicado: (2018)

A Water‐Soluble Iridium Photocatalyst for Chemical Modification of Dehydroalanines in Peptides and Proteins
por: van Lier, Roos C. W., et al.
Publicado: (2020)

Influence of Lactose on the Maillard Reaction and Dehydroalanine-Mediated Protein Cross-Linking in Casein and Whey
por: Nielsen, Søren D., et al.
Publicado: (2022)

Post-translational Introduction of d-Alanine into Ribosomally Synthesized Peptides by the Dehydroalanine Reductase NpnJ
por: Yang, Xiao, et al.
Publicado: (2015)

Synthesis of Tetrapeptides Containing Dehydroalanine, Dehydrophenylalanine and Oxazole as Building Blocks for Construction of Foldamers and Bioinspired Catalysts
por: Lenartowicz, Paweł, et al.
Publicado: (2022)

Towards Enantiomerically Pure Unnatural α-Amino Acids via Photoredox Catalytic 1,4-Additions to a Chiral Dehydroalanine
por: Oroz, Paula, et al.
Publicado: (2022)

Asymmetric Alkylation of Cyclic Ketones with Dehydroalanine via H‐Bond‐Directing Enamine Catalysis: Straightforward Access to Enantiopure Unnatural α‐Amino Acids
por: Retini, Michele, et al.
Publicado: (2022)

Modulable Photocatalyzed Strategies for the Synthesis of α-C-Glycosyl Alanine Analogues via the Giese Reaction with Dehydroalanine Derivates
por: Poletti, Lorenzo, et al.
Publicado: (2023)

Light-initiated 1,3-dipolar cycloaddition between dehydroalanines and tetrazoles: application to late-stage peptide and protein modifications
por: Zhang, Mengqian, et al.
Publicado: (2023)

Selective Modification of Ribosomally Synthesized and Post‐Translationally Modified Peptides (RiPPs) through Diels–Alder Cycloadditions on Dehydroalanine Residues
por: de Vries, Reinder H., et al.
Publicado: (2019)

Development in Maillard Reaction and Dehydroalanine Pathway Markers during Storage of UHT Milk Representing Differences in Casein Micelle Size and Sedimentation
por: Aguilera-Toro, Miguel, et al.
Publicado: (2022)

Micellar effects and analytical applications of nitro substitution in 4-Nitro-N-alkyl-1,8-naphthalimide by cysteine derivatives
por: Martins, V.S., et al.
Publicado: (2020)

Asymmetric Synthesis of 4,4‐(Difluoro)glutamic Acid via Chiral Ni(II)‐Complexes of Dehydroalanine Schiff Bases. Effect of the Chiral Ligands Structure on the Stereochemical Outcome
por: Tokairin, Yoshinori, et al.
Publicado: (2020)

Site-Specific Antibody Conjugation to Engineered Double Cysteine Residues
por: Zhou, Qun, et al.
Publicado: (2021)

Site-Specific Bioconjugation through Enzyme-Catalyzed Tyrosine–Cysteine Bond Formation
por: Lobba, Marco J., et al.
Publicado: (2020)

Cysteine‐Assisted Click‐Chemistry for Proximity‐Driven, Site‐Specific Acetylation of Histones
por: Afonso, Cláudia F., et al.
Publicado: (2022)

2-Amino-5-nitrobenzoic acid
por: Odabaşoğlu, Hakkı Yasin, et al.
Publicado: (2012)

Cysteine Dioxygenase Regulates the Epithelial Morphogenesis of Mammary Gland via Cysteine Sulfinic Acid
por: Zhao, Jianjun, et al.
Publicado: (2019)

Crystal structures of the two isomeric hydrogen-bonded cocrystals 2-chloro-4-nitrobenzoic acid–5-nitroquinoline (1/1) and 5-chloro-2-nitrobenzoic acid–5-nitroquinoline (1/1)
por: Gotoh, Kazuma, et al.
Publicado: (2019)

SNOSite: Exploiting Maximal Dependence Decomposition to Identify Cysteine S-Nitrosylation with Substrate Site Specificity
por: Lee, Tzong-Yi, et al.
Publicado: (2011)

In Vitro and In Vivo Evaluation of Cysteine and Site Specific Conjugated Herceptin Antibody-Drug Conjugates
por: Jackson, Dowdy, et al.
Publicado: (2014)

Site-Specifically Labeled Immunoconjugates for Molecular Imaging—Part 1: Cysteine Residues and Glycans
por: Adumeau, Pierre, et al.
Publicado: (2016)

Dual-mechanistic antibody-drug conjugate via site-specific selenocysteine/cysteine conjugation
por: Nilchan, Napon, et al.
Publicado: (2019)

Crystal structures of 3-chloro-2-nitrobenzoic acid with quinoline derivatives: 3-chloro-2-nitrobenzoic acid–5-nitroquinoline (1/1), 3-chloro-2-nitrobenzoic acid–6-nitroquinoline (1/1) and 8-hydroxyquinolinium 3-chloro-2-nitrobenzoate
por: Gotoh, Kazuma, et al.
Publicado: (2019)

4-Nitroisophthalic acid
por: Luo, Yang-Hui, et al.
Publicado: (2011)

Chlorine and Nitro-Muriatic Acid
Publicado: (1822)

Nitro-Muriatic Acid in Urticaria
Publicado: (1871)

Nitro-Hydrochloric Acid in Dentistry
Publicado: (1899)

iSNO-PseAAC: Predict Cysteine S-Nitrosylation Sites in Proteins by Incorporating Position Specific Amino Acid Propensity into Pseudo Amino Acid Composition
por: Xu, Yan, et al.
Publicado: (2013)

2-Methylamino-5-nitrobenzoic acid
por: Raza, Abdul Rauf, et al.
Publicado: (2010)

2-Allyloxy-5-nitrobenzoic acid
por: Ferreira, Valquiria B. N., et al.
Publicado: (2009)

Catalytic Site Cysteines of Thiol Enzyme: Sulfurtransferases
por: Nagahara, Noriyuki
Publicado: (2011)

(E)-2-[(2-Hydroxy-5-nitrophenyl)iminiomethyl]-4-nitrophenolate
por: Hijji, Yousef M., et al.
Publicado: (2009)

iNitro-Tyr: Prediction of Nitrotyrosine Sites in Proteins with General Pseudo Amino Acid Composition
por: Xu, Yan, et al.
Publicado: (2014)

4-Aminopyridinium 4-nitrobenzoate 4-nitrobenzoic acid
por: Quah, Ching Kheng, et al.
Publicado: (2008)

Pyridinium 3-nitrobenzoate–3-nitrobenzoic acid (1/1)
por: Howarth, Alexis, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_6kctf0f0gp58j222eoamkp0339