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Development of an Antigen-Antibody Co-Display System for Detecting Interaction of G-Protein-Coupled Receptors and Single-Chain Variable Fragments

G-protein-coupled receptors (GPCRs), especially chemokine receptors, are ideal targets for monoclonal antibody drugs. Considering the special multi-pass transmembrane structure of GPCR, it is often a laborious job to obtain antibody information about off-targets and epitopes on antigens. To accelera...

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Detalles Bibliográficos
Autores principales: Zhang, Yinjie, Wu, Boyang Jason, Yu, Xiaolan, Luo, Ping, Ye, Hao, Yu, Yan, Han, Wei, Li, Jingjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125734/
https://www.ncbi.nlm.nih.gov/pubmed/33946798
http://dx.doi.org/10.3390/ijms22094711