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The Relevance of Amyloid β-Calmodulin Complexation in Neurons and Brain Degeneration in Alzheimer’s Disease

Intraneuronal amyloid β (Aβ) oligomer accumulation precedes the appearance of amyloid plaques or neurofibrillary tangles and is neurotoxic. In Alzheimer’s disease (AD)-affected brains, intraneuronal Aβ oligomers can derive from Aβ peptide production within the neuron and, also, from vicinal neurons...

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Detalles Bibliográficos
Autores principales: Poejo, Joana, Salazar, Jairo, Mata, Ana M., Gutierrez-Merino, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125740/
https://www.ncbi.nlm.nih.gov/pubmed/34067061
http://dx.doi.org/10.3390/ijms22094976