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Assessing the Role of Calmodulin’s Linker Flexibility in Target Binding
Calmodulin (CaM) is a highly-expressed Ca [Formula: see text] binding protein known to bind hundreds of protein targets. Its binding selectivity to many of these targets is partially attributed to the protein’s flexible alpha helical linker that connects its N- and C-domains. It is not well establis...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125811/ https://www.ncbi.nlm.nih.gov/pubmed/34066691 http://dx.doi.org/10.3390/ijms22094990 |