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Assessing the Role of Calmodulin’s Linker Flexibility in Target Binding

Calmodulin (CaM) is a highly-expressed Ca [Formula: see text] binding protein known to bind hundreds of protein targets. Its binding selectivity to many of these targets is partially attributed to the protein’s flexible alpha helical linker that connects its N- and C-domains. It is not well establis...

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Detalles Bibliográficos
Autores principales: Sun, Bin, Kekenes-Huskey, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125811/
https://www.ncbi.nlm.nih.gov/pubmed/34066691
http://dx.doi.org/10.3390/ijms22094990