pH and Reduction Dual-Responsive Bi-Drugs Conjugated Dextran Assemblies for Combination Chemotherapy and In Vitro Evaluation

Polymeric prodrugs, synthesized by conjugating chemotherapeutic agents to functional polymers, have been extensively investigated and employed for safer and more efficacious cancer therapy. By rational design, a pH and reduction dual-sensitive dextran-di-drugs conjugate (oDex-g-Pt+DOX) was synthesiz...

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Detalles Bibliográficos
Autores principales: Xue, Xiukun, Wu, Yanjuan, Xu, Xiao, Xu, Ben, Chen, Zhaowei, Li, Tianduo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125917/
https://www.ncbi.nlm.nih.gov/pubmed/34066882
http://dx.doi.org/10.3390/polym13091515

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125917/
https://www.ncbi.nlm.nih.gov/pubmed/34066882
http://dx.doi.org/10.3390/polym13091515

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