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pH and Reduction Dual-Responsive Bi-Drugs Conjugated Dextran Assemblies for Combination Chemotherapy and In Vitro Evaluation
Polymeric prodrugs, synthesized by conjugating chemotherapeutic agents to functional polymers, have been extensively investigated and employed for safer and more efficacious cancer therapy. By rational design, a pH and reduction dual-sensitive dextran-di-drugs conjugate (oDex-g-Pt+DOX) was synthesiz...
Autores principales: | Xue, Xiukun, Wu, Yanjuan, Xu, Xiao, Xu, Ben, Chen, Zhaowei, Li, Tianduo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125917/ https://www.ncbi.nlm.nih.gov/pubmed/34066882 http://dx.doi.org/10.3390/polym13091515 |
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