Heme Oxygenase-1 Inhibition Potentiates the Effects of Nab-Paclitaxel-Gemcitabine and Modulates the Tumor Microenvironment in Pancreatic Ductal Adenocarcinoma

SIMPLE SUMMARY: Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive malignancies. Chemotherapy has had limited success in extending the life span of patients with advanced PDAC. Thus, new treatment approaches are needed. Heme oxygenase-1 (HO-1) is a key enzyme for the protection of...

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Detalles Bibliográficos
Autores principales: Ahmad, Iman M., Dafferner, Alicia J., O’Connell, Kelly A., Mehla, Kamiya, Britigan, Bradley E., Hollingsworth, Michael A., Abdalla, Maher Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125955/
https://www.ncbi.nlm.nih.gov/pubmed/34066839
http://dx.doi.org/10.3390/cancers13092264

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125955/
https://www.ncbi.nlm.nih.gov/pubmed/34066839
http://dx.doi.org/10.3390/cancers13092264

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